Methylation, SNP’S and SOLUTIONS by Marc Harris ND, MD, PhD
November 6, 2017 Puzzle Piece
SNP’s
(pronounced “snips”) are the most common type of genetic variation
among people. Each SNP represents a difference in a single DNA building
block, called a nucleotide. Testing for and treating SNP’s with a
natural approach, is not as complicated as it used to be with new
innovations developed by Dr Marc Harris.
For a simplified testing and treating method, join us at Brimhall
Homecoming February 23-25, 2018 in Tempe, AZ. We will review the many
aspects of methylation, testing and treating, including the recently
developed muscle testing sequence. The necessary kit for testing will
be available for you to acquire at the seminar.
Dr Harris will do a Webinar with me on December 6, 2017 at 7pm MST to assist your understanding.
We will send a link for your free registry in a few days.
JB, DC
A short history from Dr Harris:
1985 - Gregor Mendel (Mendelian genetics) hybridizes a green pea
with a yellow pea and produced a green pea. Generations of kids are now
happy as they like peas: Usually the green foods many people eat.
1869 – Freidrich Mieschner discovers “nuclein” in white blood
cells made up of hydrogen oxygen phosphorus and nitrogen. Nuclein
was actually DNA
1952 Rosalind Franklin show x-r diffraction od DNA
She later dies of radiation poisoning.
1953 Francis Watson and James Crick discover
the double helix.
1961 Marshal Nirenberg discerns how DND codes for proteins.
1990 Human genome Project begins.
2003 Human Genome project completed. We only have 20,000 genes
1965 The discover of DNA methylation
Methylation: As we are developing embryonically, we are
differentiated into the body systems and cells of a human being. Once
we form 2 elbows we don’t need any more: 2 lungs, kidneys 1 liver etc.
To stop genetic production of DNA we use methylation. If methylation
is off via a SNP (Single Nucleotide Polymorphism) it can change the gene
function from 30-70%. Some homozygous SNP’s are not compatible with
life.
DNA is methylated at different locations. For example: HMT
methylates at the level of histone proteins. DMNT1 (DNA Methyl
transferase) show to contain SNPS directly related to diseases. CPG
island hypermethylation is shown in cancer cells.
Genetic SNP’s are also dependent of various minerals. If needed
minerals are not consumed there is decreased function even in a non-SNP
containing gene. This deficiency is often termed genetic
nutritioneering. In a gene with a SNP, people can be given higher
amounts of these nutrients to increase genetic function.
Folic acid is not folate. It is a synthetic form that slowly
converts to tetrhydrofolate. If there is a SNP (MTHFR) then folic acid
actually blocks folate metabolism. Folate is an essential vitamin.
Folic acid is ineffective at best, dangerous at the worst. Folate is
termed from the latin folium (meaning leaf). Folate is dense in dark leafy greens; (iceburg lettuce is not a dark leafy green).
Testing for MTHFR is useful and incomplete. If you have a
downstream SNP and you supplement Folate, you will further drive the
downstreanm SNP and people will get worse. The methylation SNP’s are a
bit like this image.
One
change and they all come tumbling down. The entirety of the pathways
must be considered. This is not as difficult as it sounds if you have
an understanding of the entire flow. The most common testing methods
are:
- Bisulfite genomic sequencing
- Methylation-sensitive restriction endonucleases
- Methylated DNA immunoprecipitation
Is
it good to test? Yes, Methylation SNP’s cause problems with
detoxification, emotional balance, successful pregnancies and
childbirths, energy, control of DNA, cancer, inflammation, diabetes,
fibromyalgia/Chronic Fatigue Syndrome, pulmonary embolism, addictive
behavior, even alcoholism, insomnia, autism or down’s syndrome, bipolar
or manic depression, allergies or multiple chemical sensitivities,
atherosclerosis, spina bifida, cleft palate, neural tube defects
multiple sclerosis and other autoimmune disorders, Hashimoto’s,
hypothyroidism, ADD or ADHD, Dementia/Alzheimer’s, schizophrenia,
snxiety, seuropathy, Lyme Disease, chronic infections, candida,
parasites and SIBO to name a few.
These pathways are depleted by most drugs, alcohol and a poor
diet. It would be helpful to test every patient because of the many
possible SNP’s and combinations.
Join us for the December 6, 2017 webinar and Homecoming 2018 on
February 23-25 in Tempe, Arizona for “The Rest of the Story.”
To register for the 2018 Homecoming Click Here
To Download the 2018 Homecoming Itinerary Click Here
Yours in Health and Wellness,
Marc Harris, ND, MD, PhD, PhD, PhD
John W Brimhall, DC, BA, BS, FIAMA, DIBAK
Marc Harris, ND, MD, PhD, PhD, PhD
John W Brimhall, DC, BA, BS, FIAMA, DIBAK
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